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Product

OmniCHO™: the
industry leading
transient expression
system

What OmniCHo™ is

OmniCHO™ is a fully optimized transfection system

No product specific customization required for high performance.

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POMNI™ Vector

Synergistic with cells, media and transfection reagent. One vector for any molecule, no customization required

OmniCHO™ Cells

Variant of CHO-K1 based SUPERCELL™ for increased transient production

OmniCHO™ Media & Feeds

Optimized for growth, transfection, and expression of OmniCHO™ Cells

ACET™ Transfection Reagent

First transfection reagent for high density CHO-K1 transfection with no toxicity

Subtitle

SUPERCELL™ CHO-K1 for
expression and CQAs

Clear sequence

The OmniCHO™ workflow — from
design to material in your lab

  1. Multi-gram per liter yields for mAbs and non mAbs

  2. Minimal handling, no special equipment

  3. Optimized for ultra-high VCD transfection

  4. Flexible harvest window for rapid production

Applications of OmniCHO™

OmniCHO™ applications across R&D to preclinical development — from early studies to production-ready material

  1. Early R&D

    • Target validation studies
    • Structural biology studies
    • Epitope mapping
    • Protein-protein interaction studies
    • Library screening of candidate molecules
    • Early-stage developability assessment
    • Generation of immunization antigens

  2. Diagnostics/Reagent Production

    • mAbs for diagnostic assays
    • Reagents for cell therapy
    • Reagents for release assays
    • Generation of immunization antigens
    • Reagents for commercial assays

  3. Lead Optimization

    • Rapid screening of protein variants
    • De novo AI mAb generation
    • AI protein engineering studies for:
    • Stability, Solubility, Aggregation, Binding
    • Comparison of molecular formats
    • Assessment of novel protein designs

  4. Preclinical Development

    • Analytical method development
    • Formulation screening
    • Stability studies
    • Process development
    • Reference standard generation
    • Animal study material production
    • Toxicology batch production (with high-yield CHOK1 systems)
Performance data

OmniCHO™ performance overview

OmniCHO™ scaleup growth across bioreactor volumes

Consistent exponential growth from shake flask to production scale, with high viable cell densities maintained through every transfer.

Nanobody Fusion
3,684
617
mAb1
3,691
460
mAb2
3,546
227
mAb3
3,152
926
mAb4
2,227
779
mAb6
1,694
276
mAb7
1,477
278
mAb8
836
260
OmniCHO Market Leader

Benefits of OmniCHO™

  • Scale Up / Down

    • Scaleup with no loss in titer in flask
    • Scaleup with no loss in titer in STR or WAVE
    • High yields even at small-scale
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  • Expression improvements

    • Exceptional performance with non-mAbs
    • Replace E Coli with OmniCHO™ for native-like mammalian antigen production
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  • Cost / Labor

    • 90% reduction in COGS compared to all other kits
    • Reduced burden on mol bio for plasmid prep
    • Automation-friendly kit
    • Reduced production scale = less burden on upstream and downstream
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  • Exceptional consistency

    • Consistent titer up to 120 generations
    • No change in expression with different complex incubation times
    • Same host CHO-K1 cells = same product quality in transient and stable cell lines
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How to order
the OmniCHO™ kit

Part # Description Contents Unit
CT-OMC-001 OmniCHO™ Starter Kit – includes everything to get started with your first OmniCHO™ production OmniCHO™ cells, pOMNI™ Vector, 1L OmniCHO™ transfection kit, 2L of OmniCHO™ media and OmniCHO™ SOP 1 kit
CT-OMC-002 1L OmniCHO™ Transfection Kit ACFT™ transfection reagent, OmniCHO™ Feed, OmniCHO™ supplements 1 L
CT-OMC-003 5L OmniCHO™ Transfection Kit ACFT™ transfection reagent, OmniCHO™ Feed, OmniCHO™ supplements 5 L
CT-OMC-004 1L OmniCHO™ Media OmniCHO™ media 1 L
CT-OMC-005 10L OmniCHO™ Media OmniCHO™ media 10 L
Frequently asked questions

Quick answers
to common questions

Quick answers about timelines, quality, and how to work with Celltheon.

View more answers

OmniCHO™ is a next-generation transient expression platform designed for high-yield recombinant protein production. Built on the SUPERCELL™ CHO-K1 foundation, OmniCHO™ empowers researchers to produce a wide range of proteins—including difficult-to-express molecules—at titers previously unattainable with transient systems.

Discuss your molecule with our scientists

We don’t workaround — we innovate
and deliver

Explore whether OmniCHO™ is the right expression platform for your specific protein format.

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